homodeletion
/ˌhoʊmoʊdɪˈliːʃən/
Word Rarity
Very rare
Frequency: Zipf frequency 0.00 in modern English
18
Scrabble Score
12
Letters
4
Syllables
9
Unique Chars
Meaning
noun
A type of chromosomal deletion where both copies (alleles) of a particular DNA sequence are lost from an individual's genome.
Countable; Uncountable
Example Sentences
- "The study identified a homodeletion in the CDKN2A gene, which is associated with an increased risk of certain cancers."
- "Define homodeletion as an operation of deleting a run of the same nucleotide and homoinsertion as an operation of inserting a run of the same nucleotide."
- "While homodeletion of CYB5D2 can be detected in both the TCGA (8/1093=0.7%) and Metabric (4/2051=0.2%) datasets, the frequency is low; nonetheless, in both cohorts homodeletion in TP53 was not detected."
- "These tumors often harbor homodeletion of Hippo core suppressors."