prion
/ˈpɹiːɒn/
Word Rarity
Rare
Frequency: Zipf frequency 2.52 in modern English
7
Scrabble Score
5
Letters
2
Syllables
5
Unique Chars
Meaning
noun
A self-propagating misfolded conformer of a protein that is responsible for a number of diseases that affect the brain and other neural tissue.
Example Sentences
- "Prion disease shares many features."
- "Prions retain deep mysteries, the foremost of which is what on earth they exist for."
- "Five public research institutions in France have imposed a 3-month moratorium on the study of prions—a class of misfolding, infectious proteins that cause fatal brain diseases—after a retired lab worker who handled prions in the past was diagnosed with Creutzfeldt-Jakob disease (CJD), the most common prion disease in humans."
Etymology
From (a reordering of) the initial letters of proteinaceous infectious particle. Coined by American neurologist and biochemist Stanley B. Prusiner in 1982.
Regional Pronunciation
- British English: /ˈpɹiːɒn/
Subject
Wiktionary places this term in Medicine.
Inflected Forms
Derived Forms
Phrases
prion disease
prion protein
bovine spongiform encephalopathy
Creutzfeldt-Jakob disease
mad cow disease
New Variant Creutzfeldt-Jakob Disease
chronic wasting disease
Antarctic prion
Frequently Paired Words
bovine spongiform encephalopathy
Creutzfeldt-Jakob disease
kuru
mad cow disease
New Variant Creutzfeldt-Jakob Disease
scrapie
chronic wasting disease
viroid