blood-brain barrier
Word Rarity
Uncommon
Frequency: 4.05 in modern English
24
Scrabble Score
17
Letters
5
Syllables
9
Unique Chars
Meaning
noun
A highly selective, semipermeable interface between the blood and the brain's interstitial fluid that regulates the movement of molecules and ions into the central nervous system.
Example Sentences
- "The brain and spinal cord are insulated by a tight cellular seal called the blood-brain barrier that prevents foreign chemicals from easily getting into the brain."
- "It’s estimated only 0.1% of antibodies circulating in the bloodstream enter the brain – this also includes the therapeutic antibodies currently used in clinical trials. An approach my team is taking is to use ultrasound to temporarily open the blood-brain barrier, which increases the uptake of Alzheimer’s drugs or antibody fragments."