topoisomerase
/ˌtɑpoʊˌaɪˈsɑməˌɹeɪs/
Word Rarity
Very rare
Frequency: Zipf frequency 1.90 in modern English
17
Scrabble Score
13
Letters
3
Syllables
9
Unique Chars
Meaning
noun
Any of several enzymes that affect the topology of DNA, especially ones that relax supercoiling.
Etymology
Etymology tree Ancient Greek τόπος (tópos) English topo- English isomer Proto-Indo-European *dwóh₁ ▲ Proto-Indo-European *trísinflu. Proto-Indo-European *dwísder. Ancient Greek διά (diá) Ancient Greek δῐᾰ- (dĭă-) Proto-Indo-European *steh₂- Proto-Indo-European *stísteh₂ti Proto-Hellenic *hístāmi Ancient Greek ῐ̔́στημῐ (hĭ́stēmĭ) Ancient Greek δῐῐ̈́στημῐ (dĭĭ̈́stēmĭ) Ancient Greek δῐᾰ́στᾰσῐς (dĭắstăsĭs) English diastase English -ase English isomerase English topoisomerase From topo- + isomerase.
Regional Pronunciation
- American English: /ˌtɑpoʊˌaɪˈsɑməˌɹeɪs/
- British English: /ˌtɒpəʊˌaɪˈsɒməˌɹeɪs/