Speakur

Word Pronunciation & Dictionary

paroxysmal nocturnal hemoglobinuria

Word Rarity Very rare

Frequency: Zipf frequency 1.28 in modern English

Syllables
parox-ys-mal noc-tur-nal he-moglobin-uria
IPA
57
Scrabble Score
33
Letters
7
Syllables
18
Unique Chars

Meaning

noun

A rare, acquired blood disorder in which a mutation in the PIGA gene causes red blood cells to lack protective surface proteins, making them vulnerable to complement-mediated destruction, leading to hemolysis, anemia, dark urine, and increased risk of blood clots.

Uncountable

Usage

Inflected Forms

PNH (abbreviation) paroxysmal nocturnal haemoglobinuria (alternative, UK)

Phrases

paroxysmal cold hemoglobinuria

Frequently Paired Words

paroxysmal cold hemoglobinuria

Synonyms

Marchiafava–Micheli syndrome

Questions

What does paroxysmal nocturnal hemoglobinuria mean?
A rare, acquired blood disorder in which a mutation in the PIGA gene causes red blood cells to lack protective surface proteins, making them vulnerable to complement-mediated destruction, leading to hemolysis, anemia, dark urine, and increased risk of blood clots.

How to pronounce paroxysmal nocturnal hemoglobinuria

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